Whisk together the flour, Creole seasoning, salt, and pepper in a large bowl.
Add the water in a steady stream while whisking until a batter forms. It should resemble a cake batter with few lumps.
Put the panko onto a plate and set aside.
In batches of six, dip the vegan shrimp into the wet batter and remove, shaking off excess batter. Set on the plate of panko breadcrumbs. Using your dry hand, toss the shrimp in the panko to coat all over and create a crust. When one batch of shrimp is coated, place on a sheet pan in a single layer. Continue working in batches until all the shrimp are coated.
Freeze the shrimp on the sheet pan for at least 3 hours until firm, or overnight.
When you are ready to cook, in a heavy pot or Dutch oven heat 3 inches of the oil until the temperature reaches 350°F, or until a pinch of flour sizzles when dropped in the oil. Line a plate with paper towels.
Fry the shrimp six at time, until they are golden brown all over, about 2½ minutes.
Remove from the oil and drain on the paper towel–lined plate. Repeat with the remaining shrimp. Serve immediately.